We may see men with low testosterone levels exhibiting symptoms such as increased abdominal fat, interrupted sleep, fatigue, decreased libido, loss of cognitive function, diminished muscle mass, mood swings and low mood, and depression. Although these are often considered normal side effects of aging, they can be more sinister. Mortality rates are 88% higher in men with low testosterone than those who tested at normal levels. Testosterone levels peak in a man’s 20’s. After that, they naturally slowly decline. We do have to be careful, because low testosterone is often considered “normal” by the time men reach their early 40’s. Often low testosterone is misdiagnosed, because anticipated values are lower than functionally optimal.
How does low testosterone happen? Environmental endocrine
disruptors, like BPA and phthalates in plastics, are extremely difficult to
avoid. Chronic stress, which 46% of men experience, can throw off the
production of hormones. Along the same vein, overtraining athletes can disturb
adrenal function. Malnutrition and overeating can also contribute to low
testosterone. Obesity, however, starts the vicious cycle of metabolic syndrome
associated with low testosterone.
Obesity and low testosterone are terrible team. While
obesity decreases the production of testosterone, low testosterone levels
increase fat around the abdomen. Abdominal fat goes hand-in-hand with metabolic
syndrome, a group of risk factors that are associated with heart disease,
stroke, and diabetes. It is thought that testosterone supplementation in
hypogonadal men may benefit body composition by decreasing abdominal fat and
increasing muscle mass as well as improve insulin sensitivity and decrease risk
of cardiovascular disease.
Unfortunately, testosterone supplementation may not be as
directly useful against metabolic syndrome as initially thought. A 2012 article
in Current Diabetes Review showed that testosterone therapy showed minimal
changed in body composition in men. However, the improved mood, higher level of
energy, and decreased fatigue experienced with testosterone treatment may
indirectly reduce the risk of metabolic syndrome by motivating men to exercise
more and consume a healthier diet!
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