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Thursday, August 25, 2016

PCOS and Soy

PCOS is a hormonal imbalance in women the leads to the formation of ovarian cysts.



Although Polycystic Ovarian Syndrome (PCOS) is one of the most common endocrine disorders in women, diagnosing it is difficult due to the wide range of diagnostic criteria used by physicians. PCOS is characterized by reproductive disorders, skin problems, insulin resistance, high blood pressure, cholesterol problems, and obesity. Many of these symptoms are related to metabolic disease. If left untreated, these health problems can lead to type 2 diabetes, heart disease, cancers, and infertility.

Supplements for PCOS Control:

  • N-actyl cysteine (NAC)
  • Casteberry
  • Cinnamon
  • Quercetin
  • Red Yeast
  • Curcumin


Recent research has suggested that these symptoms may be related to high levels of inflammation and oxidative stress in women with PCOS, with interest in using soy isoflavones in treatment for metabolic disease.  Isoflavones are a type of phytoestrogen, a plant component with estrogenic effects that can protect against hormonal and metabolic abdnormalities.

One study followed the progress of PCOS suffers who took soy isoflavones for twelve weeks to compare them to a placebo group. After the study concluded, the participants who consumed soy isoflavones saw significant decreases in insulin resistance, hormones statues, triglycerides, and markers for oxidative stress. Another study saw that Genistein, a soy complex, improved lipid and hormone profiles in PCOS patients.

Due to the nature of the symptoms associated with PCOS, such as weight gain or increased facial hair, those who suffer from it tend to experience a low quality of life. With a growing number of women seeing metabolic syndrome associated with PCOS, an effective treatment can increase both quality of life and self-esteem. Treatment with phytoestrogens such as soy isoflavones may give women a non-invasive, effective way to improve PCOS symptoms without increasing the burden of harmful side effects.   





Jamilian, M. & Asemi, Z. (2016). The Effects of Soy Isoflavones on Metabolic Status of Patients With Polycystic Ovary Syndrome. The Journal Of Clinical Endocrinology & Metabolism, jc.2016-1762. http://dx.doi.org/10.1210/jc.2016-1762

Khani, B., Mehrabian, F., Khalesi, E., & Eshraghi, A. (2016). Effect of soy phytoestrogen on metabolic and hormonal disturbance of women with polycystic ovary syndrome. J Res Med Sci, 16(3), 297-302.


Love, J., McKenzie, J., Nikokavoura, E., Broom, I., Rolland, C., & Johnston, K. (2016). The experiences of women with polycystic ovary syndrome on a very low-calorie diet. International Journal Of Women's Health, Volume 8, 299-310. http://dx.doi.org/10.2147/ijwh.s100385

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